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"What lies behind you and what lies in front of you, pales in comparison to what lies inside of you."
Ralph Waldo Emerson

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Hereditary Amyloidosis: The V122I Variant

Despite the evidence that a meaningful 3-4% of the US Black population of West African ancestry likely carries the V122I genetic mutation, hereditary TTR amyloidosis remains significantly underdiagnosed and undertreated in this population. Amyloidosis can be devastating to both patients and their families. Increased awareness of the disease, availability of testing, and FDA-approved therapies are slowly beginning to shift this dynamic. However, there is still much work to be done to close the gap between diagnosed cases and the population estimated to be affected.

Worldwide Hotspots of Hereditary ATTR Amyloidosis (ATTRv)

Transthyretin Amyloidosis, or ATTR, is considered a single disease, however the diversity in its clinical presentation is staggering. In this blog, we’ll discuss some of the most common hereditary variants and how the disease manifestation differs around the world in documented hotspots.

2022: Mackenzie’s Mission – Our Report Card

This past year was more of the same, but hitting a big milestone! With the help of so many, we continued to advance our dual mission of raising awareness and supporting research. Since we began …. For our raising awareness initiative – the Amyloidosis Speakers Bureau – we are SUPER PROUD to say we’ve given over 215 presentations to MORE THAN 10,000 medical students and residents!! For our supporting research initiative, we’ve given over $830,000!! Looking ahead, it’s all about continuing to do more of the same great work. We can’t do it without your support, passion, and shared determination to make a difference in the fight against amyloidosis. Thank you!