Dr. Morie Gertz, hematologist, professor of medicine at the Mayo Clinic in Rochester and world renowned expert in amyloidosis, provides the ABCs of AL amyloidosis. His “Weeds in the Garden” is a legendary story explaining the biology behind this disease and how mis-folded proteins are created and evolve. He concludes with how treatments seek to deal with these mis-folded proteins and the goal of improving patients’ quality of life. This is a must-watch video for healthcare professionals from an esteemed expert.
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ATTR Amyloidosis Treatments: Stabilizers and Silencers
Dr. Brett Sperry, cardiologist and director of the Cardiac Amyloidosis Program at Saint Luke’s Mid America Heart Institute, provides an excellent overview of FDA-approved ATTR amyloidosis treatments. He goes into detail about the biology behind silencers and stabilizers and exactly how they impair amyloidosis progression. In addition, he previews the future, summarizing new categories of drugs on the horizon.
Update: In November, 2024 the FDA approved Attruby (Acoramidis) for ATTR-CM (wild-type and hereditary/variant).
The future is indeed exciting!
