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ATTRwt

CRISPR/Cas9 – ATTR Clinical Trial Update

November 17, 2022

Per the National Institute of Health, “One of the most promising areas of research in recent years has been gene editing, including CRISPR/Cas9, for fixing misspellings in genes to treat or even cure many conditions.” In this piece we provide a clinical trial update for transthyretin (TTR) amyloidosis using this technology.

Filed Under: Featured News, What Is Amyloidosis Tagged With: #crispr, Amyloid cardiomyopathy, amyloidosis, amyloidosis diagnosis, amyloidosis research, amyloidosis treatment, ATTR amyloidosis, ATTRwt, hATTR

Carpal Tunnel & Amyloidosis – An Update

July 27, 2022

In the amyloidosis community, we are quickly learning that carpal tunnel syndrome can be one of the earliest symptoms/indicators of amyloidosis, sometimes presenting up to a decade before diagnosis. In addition, it is suspected that amyloidosis is not as rare as we once thought. Interestingly, carpal tunnel release surgery is helping to illustrate just that.

Filed Under: Featured News, What Is Amyloidosis Tagged With: amyloidosis, amyloidosis diagnosis, amyloidosis research, ATTR amyloidosis, ATTRwt, cardiac amyloidosis, hATTR, raising awareness, wild-type amyloidosis

ATTR-CM (cardiomyopathy) vs ATTR-PN (peripheral neuropathy)

June 23, 2022

Over the course of the past two months, we spent time discussing two of the most common hallmark symptoms of ATTR amyloidosis: cardiomyopathy and peripheral neuropathy. In this article, we’ll briefly recap both hallmark symptoms as well as bring it all together by discussing the two most common forms of ATTR amyloidosis: ATTR cardiomyopathy (ATTR-CM) and ATTR peripheral neuropathy (ATTR-PN).

Filed Under: Featured News, What Is Amyloidosis Tagged With: amyloidosis, amyloidosis diagnosis, ATTR amyloidosis, ATTR-CM, ATTR-PN, attrv, ATTRwt, cardiomyopathy, hATTR, neuropathy, polyneuropathy

Peripheral Neuropathy & Amyloidosis

May 26, 2022

Neuropathy, also known as peripheral neuropathy, is a broad term that is used to describe damage to the nerves outside of the brain and spinal cord. There are over 100 types of peripheral neuropathy that can be classified into four categories, with each type having their own symptoms and prognosis. In this article, we’ll discuss the types of peripheral neuropathy and its connection to amyloidosis.

Filed Under: Featured News, What Is Amyloidosis Tagged With: AL amyloidosis, amyloidosis, amyloidosis diagnosis, ATTR amyloidosis, attrv, ATTRwt, diagnosing amyloidosis, hATTR, Hereditary Amyloidosis, light chain amyloidosis, wild-type amyloidosis

Cardiomyopathy & Amyloidosis

April 28, 2022

Cardiomyopathy is a broad term that is used to describe disease of the heart muscle, making it difficult for the heart to provide the body with an adequate blood supply. It can lead to heart failure and even death. In this article, we’ll discuss the types of cardiomyopathy and its connection to amyloidosis.

Filed Under: Featured News, What Is Amyloidosis Tagged With: AL amyloidosis, amyloid protein, amyloidosis, amyloidosis diagnosis, ATTR amyloidosis, ATTRwt, cardiac amyloidosis, cardiomyopathy, heart failure

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