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amyloidosis research

CRISPR/Cas9 – ATTR Clinical Trial Update

Per the National Institute of Health, “One of the most promising areas of research in recent years has been gene editing, including CRISPR/Cas9, for fixing misspellings in genes to treat or even cure many conditions.” In this piece we provide a clinical trial update for transthyretin (TTR) amyloidosis using this technology.

FDA Drug Approval Process

Drugs are the lifeblood of patient treatments, and the development of new drugs is critical. Overseen by the FDA (U.S. Food and Drug Administration), in this blog we outline the phases and 12 steps required to develop and approve drugs.

Carpal Tunnel & Amyloidosis – An Update

In the amyloidosis community, we are quickly learning that carpal tunnel syndrome can be one of the earliest symptoms/indicators of amyloidosis, sometimes presenting up to a decade before diagnosis. In addition, it is suspected that amyloidosis is not as rare as we once thought. Interestingly, carpal tunnel release surgery is helping to illustrate just that.

AI, Protein Folding & Amyloidosis

AI is rapidly advancing the knowledge of protein misfolding, unlocking answers for amyloidosis which should lead to earlier diagnosis, improved treatment, and better patient survival.